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Updated: Jun 28, 2025

Efficient Construction of Drug-like Bispirocyclic Scaffolds Via Organocatalytic Cycloadditions of α-Imino γ-Lactones and Alkylidene Pyrazolones
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化学選択型ディアジン脱オマチゼーション:ピラジンの触媒的エナチオ選択型脱オマチゼーション

Devin R Ketelboeter1, Mukesh Pappoppula1, Aaron Aponick1

  • 1Center for Heterocyclic Compounds, Department of Chemistry, University of Florida, Gainesville, Florida 32611, United States.

Journal of the American Chemical Society
|April 15, 2024
PubMed
まとめ

研究者はピラジンのエナチオ選択的脱オロマ化のための新しい銅触媒法を開発し,キラルピラジンを生成した. この画期的な発見により ダイアジンへの代オロマ化化学が拡大し 価値あるキラル化合物へのアクセスを可能にしました

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