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Updated: Jun 28, 2025

Membrane Transport Processes Analyzed by a Highly Parallel Nanopore Chip System at Single Protein Resolution
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Membrane Transport Processes Analyzed by a Highly Parallel Nanopore Chip System at Single Protein Resolution

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緩衝 pH とイオン強度調整による細胞膜電泳によるネイティブマルチパストランスメブランタンパク質の急速な濃縮

Tzu-Tzu Liu1, Sin-Han Huang1, Ling Chao1

  • 1Department of Chemical Engineering, National Taiwan University, No. 1, Sec. 4, Roosevelt Rd., Taipei 10617, Taiwan.

Journal of the American Chemical Society
|April 17, 2024
PubMed
まとめ

細胞膜電解は,バッファ条件を最適化することで,グルコーストランスポーター1複合体のような膜タンパク質を素早く豊かにします. 新しい力モデルは タンパク質の移動性を説明し 固有の環境の中で 孤立と集中を助けます

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In multi-pass transmembrane proteins, the polypeptide chain crosses the membrane more than once. The transmembrane polypeptide chain either forms an α-helix or β-strand structure. α-Helix containing multi-pass transmembrane proteins are ubiquitous, whereas β-strand containing ones are mainly found in gram-negative bacteria, mitochondria, and chloroplasts.
α-Helix containing multi-pass transmembrane proteins
Multi-pass transmembrane proteins such as...
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