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Updated: Jun 28, 2025

Tumor Transplantation for Assessing the Dynamics of Tumor-Infiltrating CD8+ T Cells in Mice
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Published on: June 12, 2021

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IGSF8は先天的な免疫チェックポイントであり,がん免疫療法の標的である

Yulong Li1, Xiangyang Wu1, Caibin Sheng2

  • 1Shanghai Xunbaihui Biotechnology Co., Ltd., 3rd floor of Building 4, No. 3728, Jinke Road, Pudong New Area, Shanghai, 201203, China.

Cell
|April 24, 2024
PubMed
まとめ

腫瘍はIGSF8を通じて先天的な免疫を回避し,それは自然殺虫剤 (NK) 細胞の機能を抑制する. IGSF8を阻害すると,NK細胞の活性が増加し,腫瘍の成長が抑制され,新たな治療標的となる.

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