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Updated: May 11, 2026

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Mette Galsgaard Malle1, Ping Song1, Philipp M G Löffler2

  • 1Interdiscilinary Nanoscience Center, Aarhus University, 8000 Aarhus C, Denmark.

Journal of the American Chemical Society
|April 26, 2024
PubMed
まとめ

研究者はDNAを用いて細胞外小胞 (EV) とリポソームを融合させ,RNAの配送を改善するために新しいナノキャリア (EVL) を開発した. この技術は,合成脂質ナノ粒子 (LNP) に対してより安全な代替手段を提供することで,mRNAの読み込みと翻訳を向上させます.

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関連する概念動画

RNA Interference01:23

RNA Interference

RNA interference (RNAi) is a process in which a small non-coding RNA molecule blocks the post-transcriptional expression of a gene by binding to its messenger RNA (mRNA) and preventing the protein from being translated.
This process occurs naturally in cells, often through the activity of genomically-encoded microRNAs. Researchers can take advantage of this mechanism by introducing synthetic RNAs to deactivate specific genes for research or therapeutic purposes. For example, RNAi could be used...