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Updated: Jun 27, 2025

Recapitulation of an Ion Channel IV Curve Using Frequency Components
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Published on: February 8, 2011

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CAVIN1媒介のhERGダイナミクス:薬剤誘発の長QTにおける個体間変動の基礎となる新しいメカニズム

Zeina R Al Sayed1, Céline Pereira1, Rémi Le Borgne2

  • 1PARCC, INSERM (Z.R.A.S., C.P., C.J., N.M., J.-S.H.), Université Paris Cité, Paris, France.

Circulation
|April 29, 2024
PubMed
まとめ

薬剤誘発QT延長 (diLQT) 感受性は,hERGチャネルダイナミクスと関連しています. CAVIN1はhERGチャネル転位を調節し,QT延長薬に対する患者の感受性に影響を与えます.

キーワード:
カベオラ薬物関連副作用および副作用誘導された多能幹細胞長いQTシンドローム筋細胞,心臓

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