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Updated: Jun 27, 2025

Quantitative Analysis of Cellular Composition in Advanced Atherosclerotic Lesions of Smooth Muscle Cell Lineage-Tracing Mice
09:06

Quantitative Analysis of Cellular Composition in Advanced Atherosclerotic Lesions of Smooth Muscle Cell Lineage-Tracing Mice

Published on: February 20, 2019

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動脈硬化 は 滑らかな 筋肉 の 細胞 に よっ て 発生 する 腫瘍 の よう な 病気 です

Huize Pan1,2, Sebastian E Ho1, Chenyi Xue1

  • 1Division of Cardiology, Department of Medicine (H.P., S.E.H., C.X., J.C., Q.S.J., L.S.R., F.L., H.Z., M.P.R.), Columbia University Irving Medical Center, New York, NY.

Circulation
|April 30, 2024
PubMed
まとめ

動脈硬化では,滑らかな筋肉細胞 (SMC) が腫瘍細胞のように振る舞い,ゲノム不安定性と過剰増殖を呈する. ニラパリブのような薬で SMCの移行をターゲットにすることで この心血管疾患の治療の可能性が示されています

キーワード:
動脈硬化症心血管疾患滑らかな筋肉細胞

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