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関連する概念動画

Major Hormones and Their Functions01:27

Major Hormones and Their Functions

381
Hormones, the biochemical messengers produced by endocrine glands, are pivotal in regulating bodily functions and maintaining homeostasis. Each hormone's balance is crucial; imbalances can lead to significant physiological disruptions. Major hormones include oxytocin, cortisol, epinephrine, estrogen, testosterone, thyroxine, growth hormone, insulin, and glucagon.
Oxytocin, produced in the hypothalamus and released by the pituitary gland, plays a role in social bonding, childbirth, and...
381
Hormones of the Pituitary Gland01:27

Hormones of the Pituitary Gland

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The small, pea-sized pituitary gland is located at the base of the brain. It is crucial in regulating various bodily functions, from growth to reproduction. The gland is divided into the anterior lobe and the posterior lobe. The secretory cell clusters in the pars distalis of the anterior pituitary lobe are controlled by hypothalamic regulators and synthesize six primary hormones.
The most abundantly secreted hormone from the anterior lobe is the growth hormone, which controls overall growth by...
6.5K
The Pituitary Gland01:17

The Pituitary Gland

6.7K
The pituitary is a small endocrine organ in the sphenoid bone under the hypothalamus. Primarily, the pituitary in adults has two distinct anatomical and functional regions— the anterior and posterior lobes. During human fetal development, a third pituitary gland region called the pars intermedia atrophies and disappears. However, some of its cells migrate and exist adjacent to the anterior pituitary in adults.
6.7K
Hypoglycemia and Glucagon01:15

Hypoglycemia and Glucagon

257
Without prolonged fasting, healthy individuals maintain blood glucose levels above 3.5 mM due to a well-adapted neuroendocrine counterregulatory system that effectively prevents acute hypoglycemia, a potentially life-threatening condition. The primary clinical scenarios for hypoglycemia encompass diabetes treatment, inappropriate production of endogenous insulin or insulin-like substances by tumors, and the use of glucose-lowering agents in non-diabetic individuals. Notably, hypoglycemia in the...
257
Regulation of Hormone Secretion01:19

Regulation of Hormone Secretion

3.4K
Regulation of hormone secretion is a finely tuned orchestration driven by various types of stimuli, encompassing neural, humoral, and hormonal signals. Environmental cues instigate neural stimuli, where action potentials traverse nerve fibers to reach their designated targets. An illustrative scenario is the body's response to stress, wherein the sympathetic nervous system releases epinephrine from the adrenal glands, inducing the well-known 'fight or flight' reaction.
Humoral...
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Hypothalamic-Pituitary Axis01:37

Hypothalamic-Pituitary Axis

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The response to stress—be it physical or psychological, acute or chronic—involves activation of the Hypothalamic-Pituitary-Adrenal (HPA) axis. The HPA axis is part of the neuroendocrine system because it involves both neuronal and hormonal communication. Its function is to regulate homeostatic systems—metabolic, cardiovascular, and immune—providing the necessary means to respond to a stressor.
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関連する実験動画

Updated: Jun 26, 2025

Development of Organoids from Mouse Pituitary as In Vitro Model to Explore Pituitary Stem Cell Biology
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低垂体症

Maria Fleseriu1, Mirjam Christ-Crain2, Fabienne Langlois3

  • 1Department of Medicine, Division of Endocrinology, Diabetes and Clinical Nutrition, Oregon Health and Science University, Portland, OR, USA; Department of Neurological Surgery, Oregon Health and Science University, Portland, OR, USA; Pituitary Center, Oregon Health and Science University, Portland, OR, USA.

Lancet (London, England)
|May 12, 2024
PubMed
まとめ
この要約は機械生成です。

低垂体症は 希少な垂体ホルモンの欠乏症で 診断が不十分ですが 増加しています 診断にはホルモンの検査が含まれており 治療はホルモンの置換に 焦点を当てていますが 死亡リスクは持続する可能性があります

さらに関連する動画

Endoscopic Endonasal Trans-sphenoidal Approach: Minimally Invasive Surgery for Pituitary Adenomas
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Preparation of Mouse Pituitary Immunogen for the Induction of Experimental Autoimmune Hypophysitis
10:52

Preparation of Mouse Pituitary Immunogen for the Induction of Experimental Autoimmune Hypophysitis

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関連する実験動画

Last Updated: Jun 26, 2025

Development of Organoids from Mouse Pituitary as In Vitro Model to Explore Pituitary Stem Cell Biology
09:48

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Published on: February 25, 2022

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Endoscopic Endonasal Trans-sphenoidal Approach: Minimally Invasive Surgery for Pituitary Adenomas
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Preparation of Mouse Pituitary Immunogen for the Induction of Experimental Autoimmune Hypophysitis
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Preparation of Mouse Pituitary Immunogen for the Induction of Experimental Autoimmune Hypophysitis

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科学分野:

  • 内分泌学
  • 神経内分泌学
  • 下垂体障害

背景:

  • 甲状腺ホルモンの部分的または完全な欠乏は,様々な内分泌障害を引き起こす.
  • 低垂体症は希少で,診断が不十分で,発症率が上昇しており,しばしば垂体や下垂体の大量に起因する.
  • 遺伝子の変異や 低血球炎 感染症 創傷性脳損傷なども原因です

研究 の 目的:

  • 低垂体症の原因,臨床的特徴,診断,治療について見直す.
  • 下垂体ホルモン欠乏症の診断課題と治療戦略を強調する.
  • 複合性下垂体症の専門治療の重要性を強調する.

主な方法:

  • 低垂体症に関する文献のレビュー
  • 発症,原因,および影響を受けた下垂体軸に基づく臨床的特徴の分析.
  • 基礎ホルモンレベルと刺激検査を含む診断基準の検討
  • ホルモン置換療法とそれに関連する死亡リスクの検討

主要な成果:

  • 特定のホルモンの欠乏と発症によって,臨床表現は大きく異なります.
  • 診断は基礎ホルモン測定とダイナミックテストに依存しています.
  • ホルモンの代用療法が主な治療法です.
  • 死亡率の上昇は,特に特定の患者群では持続する可能性があります.

結論:

  • 低垂体症は 慎重に診断し ホルモン補充療法が必要です
  • 複雑な症例では,専門のセンターでの治療が推奨されます.
  • 継続的な死亡リスクに対処するために継続的な研究が必要です.