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Updated: May 8, 2026

Ex utero Electroporation and Whole Hemisphere Explants: A Simple Experimental Method for Studies of Early Cortical Development
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発達中の人間の皮質における規制要素の大幅な並列の特徴付け

Chengyu Deng1,2, Sean Whalen3, Marilyn Steyert4,5,6,7,8,9

  • 1Department of Bioengineering and Therapeutic Sciences, University of California, San Francisco, San Francisco, CA 94158, USA.

Science (New York, N.Y.)
|May 23, 2024
PubMed
まとめ

この研究では,ヒトの脳内の遺伝子調節要素をマッピングし,神経細胞の発達と病気に影響を与える何千もの活性増強剤と変異体を特定しました. 脳のオルガノイドは この研究のために 発達中の皮質を効果的にモデル化しています

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