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Updated: Jul 13, 2026

Using the E1A Minigene Tool to Study mRNA Splicing Changes
10:25

Using the E1A Minigene Tool to Study mRNA Splicing Changes

Published on: April 22, 2021

クリプティック・ブランチ・ポイントの活性化により,ヒトβ-グロービンのイントロン変異体の精密なインビトロスプライシングが可能になります

B Ruskin, J M Greene, M R Green

    Cell
    |July 1, 1985
    PubMed
    まとめ

    RNAスプライシングを調査したこの研究では,ヒトβ-グロービンのイントロン分岐点が変異しました. 結果は,スプライシングの精度が,周囲のシーケンスではなく,3'のスプライシング地点までの距離に依存していることを示しています.

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