関連する実験動画

Updated: Jun 25, 2025

A Fluorescence-Based Assay of Membrane Potential for High-Throughput Functional Study of Two Endogenous Ion Channels in Two Epithelial Cell Lines
06:59

A Fluorescence-Based Assay of Membrane Potential for High-Throughput Functional Study of Two Endogenous Ion Channels in Two Epithelial Cell Lines

Published on: June 22, 2022

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CFTR増強剤と阻害剤の構造に基づく発見

Fangyu Liu1, Anat Levit Kaplan2, Jesper Levring3

  • 1Laboratory of Membrane Biology and Biophysics, The Rockefeller University, New York, NY 10065, USA; Department of Pharmaceutical Chemistry, University of California, San Francisco, San Francisco, CA 94143, USA.

Cell
|May 29, 2024
PubMed
まとめ

研究者達は,システィック・フィブロシス 経膜伝導性調節体 (CFTR) タンパク質を強化したり,ブロックしたりできる新しい分子を発見しました. これらの発見は 胞性線維症と分泌性下痢の新たな治療法となる可能性があります

キーワード:
ABCトランスポーターアニオンチャンネル阻害剤大規模なドッキングリガンド発見パンチエーター

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