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Updated: Jun 24, 2025

Characterization of Functionally Associated miRNAs in Glioblastoma and their Engineering into Artificial Clusters for Gene Therapy
09:40

Characterization of Functionally Associated miRNAs in Glioblastoma and their Engineering into Artificial Clusters for Gene Therapy

Published on: October 4, 2019

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精密腫瘍治療のための誘導リボヌクレアースターゲティングキメラによるG-クアドルプレックスmRNAの静止

Yuan Zhang1, Lingyan Wang1, Fenglin Wang1

  • 1State Key Laboratory of Chemo/Bio-Sensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Changsha, Hunan 410082, China.

Journal of the American Chemical Society
|June 4, 2024
PubMed
まとめ

誘導性RIBOTAC (iRIBOTAC) は,がん治療のためのG四重複 (G4) RNAの標的分解を可能にします. この新しいアプローチは,精密なG4RNAサイレンシングと腫瘍抑制のためのバイオオートゴーナルまたは細胞特異のトリガーを使用します.

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