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Updated: Jun 24, 2025

Investigating Aortic Valve Calcification via Isolation and Culture of T Lymphocytes using Feeder Cells from Irradiated Buffy Coat
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Investigating Aortic Valve Calcification via Isolation and Culture of T Lymphocytes using Feeder Cells from Irradiated Buffy Coat

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大動脈弁の狭窄は細胞外ヘモグロビンの蓄積と全身内皮機能不全を引き起こす

Christine Quast1, Florian Bönner1, Amin Polzin1,2

  • 1Department of Cardiology, Pulmonology and Vascular Medicine, University Hospital and Medical Faculty, Heinrich Heine University, Düsseldorf, Germany (C.Q., F.B., A.P., V.V., R.C., I.G.P., S.P., N.K., M. Nankinova, N.S., E.Z., J.J., F.K., J.H., S.W., K.B., P.L., S. Zako, R.E., C.J., N.G., M.M.C.-K., T.Z., M.K.).

Circulation
|June 5, 2024
PubMed
まとめ

大動脈狭窄症 (AS) は,血中ヘモグロビンを増加させ,窒素酸化物 (NO) を消費することによって,内皮機能障害を引き起こす. トランスキャテーター大動脈弁置換 (TAVR) は,血液の流れを改善することで,内皮機能を回復します.

キーワード:
大動脈弁の狭窄エンドセリウムヘモグロビン磁気共鳴画像検査窒素酸化物トランスキャテーターによる大動脈弁の置換

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