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Updated: Jun 24, 2025

Constructing Cyclic Peptides Using an On-Tether Sulfonium Center
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Constructing Cyclic Peptides Using an On-Tether Sulfonium Center

Published on: September 28, 2022

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非リボソームペプチド合成酵素のモジュール論理にインスパイアされた急速なペプチドサイクル

Yaoyu Ding1, Edward Lambden1, Jessica Peate1

  • 1Department of Chemistry, Faculty of Natural, Mathematical, and Engineering Sciences, King's College London, Britannia House, 7 Trinity Street, London SE1 1DB, U.K.

Journal of the American Chemical Society
|June 6, 2024
PubMed
まとめ

新しい化学的方法により,複雑な非リボソーム循環ペプチド (NRcP) とその類似物を迅速に合成する. このマクロラクタマイゼーションの突破は 医薬品の発見と これらの重要な治療用天然製品の研究を 加速させています

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