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Updated: Jun 24, 2025

A New Screening Method for the Directed Evolution of Thermostable Bacteriolytic Enzymes
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Published on: November 7, 2012

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プロトグロビン の 方向づけ られ た 進化 は,酵素 の 電気 場 を 最適 に する

Shobhit S Chaturvedi1, Santiago Vargas1, Pujan Ajmera1

  • 1Department of Chemistry and Biochemistry, University of California, Los Angeles, California 90095, United States.

Journal of the American Chemical Society
|June 7, 2024
PubMed
まとめ

誘導進化 (DE) は,酵素の計算設計が失敗したところで成功する. 私たちの研究は,DEが酵素の電場を変化させ,反応メカニズムに影響することによって,効率的なカルベンの転送を可能にします.

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