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Polymer Classification: Crystallinity01:21

Polymer Classification: Crystallinity

2.8K
Unlike ionic or small covalent molecules, polymers do not form crystalline solids due to the diffusion limitations of their long-chain structures. However, polymers contain microscopic crystalline domains separated by amorphous domains.
Crystalline domains are the regions where polymer chains are aligned in an orderly manner and held together in proximity by intermolecular forces. For example, chains in the crystalline domains of polyethylene and nylon are bound together by van der Waals...
2.8K
Polymers02:34

Polymers

35.7K
The word polymer is derived from the Greek words “poly” which means “many” and “mer” which means “parts”. Polymers are long chains of molecules composed of repeating units of smaller molecules, known as monomers. They either occur naturally, such as DNA and proteins, or can be constructed synthetically, like plastics. They have varied structural characteristics, such as linear chains, branched chains, or complex networks, that contribute to the...
35.7K
Anionic Chain-Growth Polymerization: Overview01:20

Anionic Chain-Growth Polymerization: Overview

2.1K
The polymerization process that involves carbanion as an intermediate is called anionic polymerization. It is also a type of addition or chain-growth polymerization. Anionic polymerization gets initiated by a strong nucleophile such as an organolithium or a Grignard reagent. The most commonly used initiator for anionic polymerization is butyl lithium. Monomers involved in anionic polymerization must possess a vinyl group bonded to one or two electron-withdrawing groups. For instance,...
2.1K
Nucleic Acid Structure01:25

Nucleic Acid Structure

6.1K
The pentose sugar in DNA is deoxyribose, while in RNA the pentose sugar is ribose. The difference between the sugars is the presence of the hydroxyl group on the ribose's second carbon and a hydrogen on the deoxyribose's second carbon. The phosphate residue attaches to the hydroxyl group of the 5′ carbon of one sugar and the hydroxyl group of the 3′ carbon of the sugar of the next nucleotide, which forms  a 5′ to 3′ phosphodiester linkage.
DNA Structure
DNA...
6.1K
ATP and Macromolecule Synthesis01:28

ATP and Macromolecule Synthesis

5.6K
Biological macromolecules are organic compounds, predominantly composed of carbon atoms. The carbon atoms are covalently bonded with hydrogen, oxygen, nitrogen, and other minor elements. There are four major biological macromolecule classes: carbohydrates, lipids, proteins, and nucleic acids.
Most macromolecules are composed of single subunits, or building blocks, called monomers. The monomers combine with each other using covalent bonds to form larger molecules known as polymers.
Conversion of...
5.6K

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関連する実験動画

Updated: Jun 24, 2025

Functional Surface-immobilization of Genes Using Multistep Strand Displacement Lithography
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Functional Surface-immobilization of Genes Using Multistep Strand Displacement Lithography

Published on: October 25, 2018

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復元可能なガラス型ポリマーネットワークにおける可逆核酸貯蔵

Elisabeth Prince1, Ho Fung Cheng1, James L Banal2

  • 1Department of Chemistry, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, Massachusetts 02139, United States.

Journal of the American Chemical Society
|June 12, 2024
PubMed
まとめ

新しいDNA保存方法であるThermoset-REinforced Xeropreservation (T-REX) は,ガラスのようなポリマーに遺伝物質を保存しています. この低コストで効率的な技術は 長期にわたる核酸の安定性のために 冷蔵庫や危険な化学物質を避けます

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Fabricating Degradable Thermoresponsive Hydrogels on Multiple Length Scales via Reactive Extrusion, Microfluidics, Self-assembly, and Electrospinning
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Fabricating Degradable Thermoresponsive Hydrogels on Multiple Length Scales via Reactive Extrusion, Microfluidics, Self-assembly, and Electrospinning

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Plasmid-derived DNA Strand Displacement Gates for Implementing Chemical Reaction Networks
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Plasmid-derived DNA Strand Displacement Gates for Implementing Chemical Reaction Networks

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関連する実験動画

Last Updated: Jun 24, 2025

Functional Surface-immobilization of Genes Using Multistep Strand Displacement Lithography
11:05

Functional Surface-immobilization of Genes Using Multistep Strand Displacement Lithography

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Fabricating Degradable Thermoresponsive Hydrogels on Multiple Length Scales via Reactive Extrusion, Microfluidics, Self-assembly, and Electrospinning
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Fabricating Degradable Thermoresponsive Hydrogels on Multiple Length Scales via Reactive Extrusion, Microfluidics, Self-assembly, and Electrospinning

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Plasmid-derived DNA Strand Displacement Gates for Implementing Chemical Reaction Networks
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Plasmid-derived DNA Strand Displacement Gates for Implementing Chemical Reaction Networks

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科学分野:

  • バイオテクノロジー
  • 材料科学
  • ゲノミクス

背景:

  • DNAシーケンシングコストの低下は 核酸保存の需要を増加させます
  • 現在の方法は エネルギー密集した冷却チェーンと 危険な化学物質に依存しています
  • 化石の保存は DNAの保存に 新しいアプローチを促しました

研究 の 目的:

  • 核酸の長期保存のための安定した,低コストで効率的な方法を開発する.
  • 伝統的な冷蔵庫の限界を乗り越えるために
  • DNAの保存と回収を 良性反応剤で可能にします

主な方法:

  • 解体可能なガラスのようなポリマーネットワークを用いたThermoset-REinforced Xeropreservation (T-REX) を開発した.
  • 効率的なDNA封じ込めと水分から有機への移行のためのポリプレックスを作成しました.
  • ポリマー形成のための組み込みのイニシアター,モノマー,クロスリンクヤー,および分割可能なコモノマー.

主要な成果:

  • 数時間以内に様々な長さのスケール (数十の塩基からギガ塩基まで) でDNAを封じ込めました.
  • 無害な反応剤を用いたDNA抽出が実証され,シリカ基の方法では有害なフッ素酸と対比する.
  • 継続的な電気や冷却チェーンを必要とせずに効率的な核酸保存を達成しました.

結論:

  • T-REXは従来の低温核酸貯蔵に適した代替手段です
  • この方法は効率的で費用対効果が高く,より安全な反応剤を用いてDNAを復元します.
  • T-REXは合成生物学,ゲノミクス,デジタル情報保存などに 応用できる可能性があります