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Updated: Apr 28, 2026

A Tandem Liquid Chromatography–Mass Spectrometry-based Approach for Metabolite Analysis of Staphylococcus aureus
08:03

A Tandem Liquid Chromatography–Mass Spectrometry-based Approach for Metabolite Analysis of Staphylococcus aureus

Published on: March 28, 2017

10.1K

メタボロミクスパイプラインは,血流感染症における微生物の代謝を強調する

Jared R Mayers1, Jack Varon2, Ruixuan R Zhou3

  • 1Division of Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA 02115, USA; Harvard Medical School, Boston, MA 02115, USA; Department of Chemistry and Chemical Biology, Harvard University, Cambridge, MA 02138, USA.

Cell
|June 17, 2024
PubMed
まとめ

研究者らは,血流感染症で アセチル化されたポリアミンを産生する 細菌酵素である SpeG を特定しました. SpeGの抑制は病原体の成長を遅らせ,抗生物質の侵入を増加させることで抗生物質耐性を克服します.

キーワード:
N-アセチルプートレスチン抗生物質に対する耐性ディアセチルスペルミジンメタボロミクスポリアミン/ダイアミンアセチルトランスフェラーゼポリアミンセプシス

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