関連する実験動画

Updated: Jun 23, 2025

Visualization of DNA Repair Proteins Interaction by Immunofluorescence
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Visualization of DNA Repair Proteins Interaction by Immunofluorescence

Published on: June 26, 2020

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複製結合DNA断裂の構造と修復

Raphael Pavani1, Veenu Tripathi1, Kyle B Vrtis2

  • 1Laboratory of Genome Integrity, National Cancer Institute, NIH, Bethesda, MD, USA.

Science (New York, N.Y.)
|June 20, 2024
PubMed
まとめ

CRISPR-Cas9酵素は 複製フォークが DNA単一鎖の断裂と どのように相互作用するかを明らかにします 修復されていない断裂は二重鎖断裂を引き起こし,がんゲノムの安定性および同種の再結合修復 (HR) 経路に影響を与えます.

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Characterizing DNA Repair Processes at Transient and Long-lasting Double-strand DNA Breaks by Immunofluorescence Microscopy08:31

Characterizing DNA Repair Processes at Transient and Long-lasting Double-strand DNA Breaks by Immunofluorescence Microscopy

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Using Next Generation Sequencing to Identify Mutations Associated with Repair of a CAS9-induced Double Strand Break Near the CD4 Promoter06:59

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