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Updated: Jun 23, 2025

A Streamlined Approach for Mass Spectrometry-Based Proteomics Using Selected Tissue Regions
09:00

A Streamlined Approach for Mass Spectrometry-Based Proteomics Using Selected Tissue Regions

Published on: April 18, 2025

483

パンガンプロテオゲノミクスは治療標的の範囲を拡大する

Sara R Savage1, Xinpei Yi1, Jonathan T Lei1

  • 1Lester and Sue Smith Breast Center, Baylor College of Medicine, Houston, TX 77030, USA; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA.

Cell
|June 25, 2024
PubMed
まとめ

この研究は,1,000人以上の癌患者のタンパク質遺伝学データを統合することによって,新しい治療標的を特定しています. この発見は,薬効性のあるタンパク質依存性を明らかにし,がん治療の開発にネオアンチゲンを優先する.

キーワード:
パンガン, プロテオゲノミクス, 薬物標的, プロテオミクス, 合成的致死性, ネオアンチゲン, 腫瘍アンチゲン, データ統合

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