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Updated: Jun 22, 2025

Protocol for the Synthesis of Ortho-trifluoromethoxylated Aniline Derivatives
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TMSCF3を最大限に活用する:アミドの脱酸素トリフローロメチル化/シリレーション

Yuxiao Wang1, Shi-Jun Li2, Feng Jiang1

  • 1State Key Laboratory of Organometallic Chemistry and Shanghai Hongkong Joint Laboratory in Chemical Synthesis, Center for Excellence in Molecular Synthesis, Shanghai Institute of Organic Chemistry, University of Chinese Academy of Sciences, Chinese Academy of Sciences, 345 Lingling Road, Shanghai 200032, China.

Journal of the American Chemical Society
|July 3, 2024
PubMed
まとめ

この研究では,シリル基とトリフローロメチル基の両方をアミンに添加するために (トリフローロメチル) トリメチルシラン (TMSCF3) を使用する新しい方法が導入されています. この効率的なプロセスは,価値あるα-シリル-α-トリフルオロメチルアミンを生成します.

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