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Updated: Jun 22, 2025

Production of Pseudotyped Particles to Study Highly Pathogenic Coronaviruses in a Biosafety Level 2 Setting
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Production of Pseudotyped Particles to Study Highly Pathogenic Coronaviruses in a Biosafety Level 2 Setting

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TMPRSS2とグリカン受容体は,コロナウイルスの侵入を相乗的に促進する

Haofeng Wang1, Xiaoce Liu1, Xiang Zhang2

  • 1Shanghai Institute for Advanced Immunochemical Studies and School of Life Science and Technology, ShanghaiTech University, Shanghai 201210, China; Shanghai Clinical Research and Trial Center, Shanghai 201210, China.

Cell
|July 4, 2024
PubMed
まとめ

人間の新型コロナウイルスHKU1は,細胞の侵入に作用するシネジスティックなメカニズムを使用しています. シアログリカンがスパイクタンパク質に結合すると,形状の変化が起こり,TMPRSS2受容体がウイルスの侵入を認識できる.

キーワード:
HCoV-HKU1についてTMPRSS2 についてグリカン受容体タンパク質受容体ウイルスの侵入

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