エンジニアリングされたサイトクロームP450触媒バイアリル結合反応によって活性化されたフッ素化ミコサイクロシンの化学酵素合成

Shuo-Han Li1, Xue Zhang2, Ze-Long Mei1

  • 1Department of Chemistry, Tianjin Key Laboratory of Molecular Optoelectronic Sciences, Frontiers Science Center for Synthetic Biology (Ministry of Education), Tianjin University, Tianjin 300072, China.

まとめ

研究者は新しいフッ素化天然製品を作るため サイトクロームP450酵素を設計しました このハイブリッドアプローチは,潜在的薬学的な利点を持つフッ素代用ミコサイクロシン誘導体の合成を可能にします.

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