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Updated: Jun 21, 2025

Stem Cell-Derived Viral Ag-Specific T Lymphocytes Suppress HBV Replication in Mice
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Stem Cell-Derived Viral Ag-Specific T Lymphocytes Suppress HBV Replication in Mice

Published on: September 25, 2019

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肝臓免疫レオスタットは,慢性 HBV 感染症における CD8 T 細胞免疫を調節する

Miriam Bosch1, Nina Kallin1, Sainitin Donakonda1

  • 1Institute of Molecular Immunology, School of Medicine and Health, Technical University of Munich (TUM), Munich, Germany.

Nature
|July 10, 2024
PubMed
まとめ

慢性B型肝炎 (HBV) は,肝臓の免疫レオスタットによってCD8T細胞を損なう. 強化されたcAMP-PKA信号はCREMではなく,T細胞機能不全を引き起こし,HBVのクリアランスを阻害する.

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