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新石器時代の農家の6世代に渡って 繰り返された疫病感染
Frederik Valeur Seersholm1, Karl-Göran Sjögren2, Julia Koelman3
1Lundbeck Foundation GeoGenetics Centre, Globe Institute, University of Copenhagen, Copenhagen, Denmark. frederikseersholm@gmail.com.
Nature
|July 10, 2024
まとめ
古代ゲノミクスは スカンジナビアで広範囲に広がった 新石器時代のペストを明らかにし 3つの異なるイベントで広がりました この研究は新石器時代の初期における 病気の伝染と社会構造を再構築しています
科学分野:
- パレオゲノミクス
- 考古遺伝学
- 流行病学について
背景:
- ヨーロッパ新石器時代の衰退 (5,3004,900 カル) 農業危機や病気などの原因について議論しています.
- この人口変化における病原体,特にペストの役割は不明である.
研究 の 目的:
- 古代ゲノミクスを用いて新石器時代の衰退の原因を調査する
- 新石器時代のスカンジナビアにおける 病原菌の拡散,社会的組織,そして親族の構造を再構築する.
主な方法:
- スカンジナビア新石器時代の 108人の古代DNAの分析
- 祖先と病原菌の感染を推論するための 集団規模の古代ゲノミクス
- 疫病ゲノムとYersinia pseudotuberculosisの進化を再構築するための変異グラフベースのパンゲノミクス.
主要な成果:
- 新石器時代の疫病 (Yersinia pseudotuberculosis) は広範囲に広がり,サンプル集団の少なくとも17%が長距離で感染した.
- 疫病は約120年にわたって 3つの異なる感染症で広がりました
- 4つの多世代血統の再構築により,父系社会組織と女性外婚の証拠が明らかになった.
結論:
- 古代ゲノミクスは 新石器時代の衰退に寄与した 広範囲にわたる疫病の直接的な証拠を提供します
- この研究は,新石器時代のペストの伝播動態と,スカンジナビアの住民への影響を明らかにしています.
- 発見は新石器時代の社会構造の洞察力を提供し,父系組織や結婚パターンを含む.
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