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Updated: Jun 21, 2025

Phage-mediated Delivery of Targeted sRNA Constructs to Knock Down Gene Expression in E. coli
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RNAとDNAを結合するヘリックス・ターン・ヘリックスタンパク質によるファグの抗CRISPR制御

Nils Birkholz1,2,3,4, Kotaro Kamata1,2, Maximilian Feussner5

  • 1Department of Microbiology and Immunology, University of Otago, Dunedin, New Zealand.

Nature
|July 10, 2024
PubMed
まとめ

新しい調節タンパク質であるAca2は,そのヘリックス・ターン・ヘリックス・ドメインを使用して,DNAとRNAの両方の結合によってファグの抗CRISPR遺伝子発現を制御し,感染中に毒性の過剰発現を防ぐ.

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