スパマレトロウイルスの統合された冷凍EM構造は,王国間の進化的関係と,アセンブリとウイルスの侵入の分子基盤を明らかにします

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Updated: Jun 21, 2025

Averaging of Viral Envelope Glycoprotein Spikes from Electron Cryotomography Reconstructions using Jsubtomo
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Averaging of Viral Envelope Glycoprotein Spikes from Electron Cryotomography Reconstructions using Jsubtomo

Published on: October 21, 2014

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Thomas Calcraft1, Nicole Stanke-Scheffler2, Andrea Nans3

  • 1Structural Biology of Cells and Viruses Laboratory, The Francis Crick Institute, 1 Midland Road, London NW1 1AT, UK.

Cell
|July 16, 2024
PubMed
まとめ

構造研究は,発泡性ウイルス (FV) のカプシドとエンベロープのグリコタンパク質の古代構造を明らかにする. この研究は,原型発泡性ウイルス (PFV) のベクトルを用いたレトロウイルス進化と潜在的な遺伝子療法に関する新しい洞察を提供します.

キーワード:
カプシドクリオ・エムクリオ・エット発泡ウイルス膜融合パラミクソウイルス準同等性について受容体への結合レトロウイルスウイルスの進化

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