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Updated: Jun 20, 2025

Lipid Supplementation for Longevity and Gene Transcriptional Analysis in Caenorhabditis elegans
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Published on: December 9, 2022

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IL-11のシグナル伝達抑制は,哺乳類の健康と寿命を延長する

Anissa A Widjaja1, Wei-Wen Lim2,3, Sivakumar Viswanathan2

  • 1Cardiovascular and Metabolic Disorders Program, Duke-National University of Singapore Medical School, Singapore, Singapore. anissa.widjaja@duke-nus.edu.sg.

Nature
|July 17, 2024
PubMed
まとめ

炎症を誘発するサイトカインであるインタールウィキン-11 (IL-11) は老化と寿命に悪影響を及ぼします. IL- 11を抑制することで,マウスの健康状態が改善され,骨の脆弱性が減少し,寿命が大幅に延長されました.

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