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Updated: Jun 20, 2025

Constructing Cyclic Peptides Using an On-Tether Sulfonium Center
07:11

Constructing Cyclic Peptides Using an On-Tether Sulfonium Center

Published on: September 28, 2022

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不自然なペプチドマクロサイクルをRh (III) -触媒化カルボアミデーションによって作り出す

Christopher W Lamartina1, Cassandra A Chartier1, Jillian M Hirano1

  • 1Department of Chemistry, Columbia University, New York, New York 10027, United States.

Journal of the American Chemical Society
|July 18, 2024
PubMed
まとめ

Rh (III) 触媒によるカルボアミデーションは,複雑な循環ペプチドの効率的な合成を可能にします. この方法は非正規のアミノ酸を組み込み,非自然なフェニララニンおよびチロシン誘導体を高ダイアステロ選択性で生成します.

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