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Updated: Jun 19, 2025

Solid-phase Synthesis of [4.4] Spirocyclic Oximes
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Published on: February 6, 2019

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(-) - ラウボミンBの総合成 ストレインプロモートされた内分子サイクロプロパネーション

Jake M Aquilina1, Ankush Banerjee1, Gabriel N Morais1,2

  • 1Department of Biochemistry, UT Southwestern Medical Center, 5323 Harry Hines Blvd., Dallas, Texas 75390, United States.

Journal of the American Chemical Society
|July 23, 2024
PubMed
まとめ

研究者は,サイクロプロパン環を備えたインドルアルカロイドである (-) - ラウボミンBの最初の完全な合成を達成しました. この戦略では,テトラサイクルのN-スルフォニルトリアゾールの分子内サイクロプロパネーションを用いて,標的分子を11段階で生成した.

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