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Updated: Jun 19, 2025

Tumor Transplantation for Assessing the Dynamics of Tumor-Infiltrating CD8+ T Cells in Mice
07:36

Tumor Transplantation for Assessing the Dynamics of Tumor-Infiltrating CD8+ T Cells in Mice

Published on: June 12, 2021

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ネオアンチゲン特異の細胞毒性Tr1 CD4 T細胞ががん免疫治療を抑制する

Hussein Sultan1,2, Yoshiko Takeuchi1,2, Jeffrey P Ward3

  • 1Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO, USA.

Nature
|July 24, 2024
PubMed
まとめ

高用量のMHC- II新抗原ワクチンは, dendritic 細胞を殺すことで抗腫瘍免疫を抑制する細胞毒性1型調節性T (Tr1) 細胞を誘発する. この抑制を阻害する戦略は 潜在的ながん治療の方法を提供します

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Genes usually encode proteins necessary for the proper functioning of a healthy cell. Mutations can often cause changes to the gene expression pattern, thereby altering the phenotype.
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