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Updated: Jun 19, 2025

Controlled Photoredox Ring-Opening Polymerization of O-Carboxyanhydrides Mediated by Ni/Zn Complexes
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Controlled Photoredox Ring-Opening Polymerization of O-Carboxyanhydrides Mediated by Ni/Zn Complexes

Published on: November 21, 2017

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後期段階 C ((sp2) -C ((sp3) ニッケル酸化添加複合体による多様化

Carlota Odena1,2, Tomás G Santiago1, María Lourdes Linares3

  • 1Institute of Chemical Research of Catalonia (ICIQ), The Barcelona Institute of Science and Technology, Avenida Països Catalans 16, 43007 Tarragona, Spain.

Journal of the American Chemical Society
|July 25, 2024
PubMed
まとめ

ニッケル酸化添加複合体 (Ni-OAC) は,薬剤発見のための新しいプラットフォームを提供します. このアプローチは,設計・製造・テスト・分析のサイクルを加速させ,強化されたC ((sp3) 分子を有するリード候補を迅速に生成します.

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Efficient Synthesis of All-Carbon Quaternary Centers via the Conjugate Addition of Functionalized Monoorganozinc Bromides07:50

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Diols are compounds with two hydroxyl groups. In addition to syn dihydroxylation, diols can also be synthesized through the process of anti dihydroxylation. The process involves treating an alkene with a peroxycarboxylic acid to form an epoxide. Epoxides are highly strained three-membered rings with oxygen and two carbons occupying the corners of an equilateral triangle. This step is followed by ring-opening of the epoxide in the presence of an aqueous acid to give a trans diol.
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