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Updated: Jul 28, 2026

Induction of Invasive Transitional Cell Bladder Carcinoma in Immune Intact Human MUC1 Transgenic Mice: A Model for Immunotherapy Development
11:02

Induction of Invasive Transitional Cell Bladder Carcinoma in Immune Intact Human MUC1 Transgenic Mice: A Model for Immunotherapy Development

Published on: October 30, 2013

免疫グロブリン増強剤によって駆動されるc-myc腫瘍遺伝子は,トランスゲンマウスのリンパ性悪性腫瘍を誘発する

J M Adams, A W Harris, C A Pinkert

    Nature
    |December 12, 1985
    PubMed
    まとめ

    細胞のmycオンコゲンを持つトランス遺伝子マウスは致命的なリンパ腫を発症し,B細胞がんにおけるc-mycの役割を示している. これらのマウスは,リンパ腫とB細胞の発達を研究するための貴重なモデルです.

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