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Updated: Jun 20, 2026

An Ecdysone Receptor-based Singular Gene Switch for Deliberate Expression of Transgene with Robustness, Reversibility, and Negligible Leakiness
06:21

An Ecdysone Receptor-based Singular Gene Switch for Deliberate Expression of Transgene with Robustness, Reversibility, and Negligible Leakiness

Published on: May 7, 2018

ユーカリオットのトランスクリプション活性化剤で,プロカリオットの抑制器のDNA特異性を有する

R Brent, M Ptashne

    Cell
    |December 1, 1985
    PubMed
    まとめ

    研究者は,DNAを結合し,酵母における遺伝子転写を活性化するハイブリッドタンパク質,LexA-GAL4を作成しました. これは,プロカリオットDNA結合ドメインが,転写活性化を維持しながら,酵母ドメインを置き換えることができることを示しています.

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