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Updated: Jun 17, 2025

Author Spotlight: Dendritic Cells Maturation Using Sialidases-Based Enzymatic Treatment of the Cell Surface
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グリコスフィンゴリピド合成は,KRAS誘発がんにおける免疫回避を媒介する

Mariluz Soula1, Gokhan Unlu1, Rachel Welch1

  • 1Laboratory of Metabolic Regulation and Genetics, The Rockefeller University, New York, NY, USA.

Nature
|August 7, 2024
PubMed
まとめ

癌細胞は免疫攻撃を回避するために スフィンゴリピド合成を利用します この経路を阻害すると,抗癌免疫力が強化され,治療法と連携し,ガンに対する免疫回避の主要標的としてグリコスフィンゴリピドが明らかになります.

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