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Updated: Jun 16, 2025

Constructing Cyclic Peptides Using an On-Tether Sulfonium Center
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Published on: September 28, 2022

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ペプチドとタンパク質の制御された反転性N端末改変

Zeng Lin1,2,3, Bo Liu1,2, Mengru Lu1,2,3

  • 1School of Pharmaceutical Science and Technology, Hangzhou Institute of Advanced Study, Hangzhou 310024, China.

Journal of the American Chemical Society
|August 15, 2024
PubMed
まとめ

研究者らは,パラジウム触媒を用いた新しい可逆性N端タンパク質改変法を開発した. この戦略により,制御されたタンパク質の"ケージング"と"デカージング"が可能になり,精密なタンパク質機能の研究と化学生物学における応用が可能となる.

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