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Updated: Jun 16, 2025

Pull-down of Calmodulin-binding Proteins
07:51

Pull-down of Calmodulin-binding Proteins

Published on: January 23, 2012

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カルモジュリノパシーに対するアンチセンスオリゴヌクレオチド療法

Raul H Bortolin1, Farina Nawar1, Chaehyoung Park1

  • 1Department of Cardiology (R.H.B., F.N., C.P., M.A.T., M.P., M.E.S., P.W., J.C., F.L., C.L., P.B., E.M.K., D.Y., N.P., T.S., Q.M., D.J.A., V.J.B., W.T.P.).

Circulation
|August 19, 2024
PubMed
まとめ

特定のカルモジュリン遺伝子を標的にするアンチセンスオリゴヌクレオチド (ASO) は,遺伝性不律症候群の治療に有望である. このアプローチは,カルモジュリン濃度を損なうことなく,モデルにおける心臓機能を効果的に正常化させました.

キーワード:
アンチセンス オリゴヌクレオチドカルシウム長いQTシンドローム精密医療短心,心室性

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