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Updated: Jun 15, 2025

Generation of Orthotopic Pancreatic Tumors and Ex vivo Characterization of Tumor-Infiltrating T Cell Cytotoxicity
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T細胞の腫瘍誘導メガモレクルの合成と活性

Sraeyes Sridhar1, Justin A Modica1, Daniel J Sykora1

  • 1Department of Biomedical Engineering, Northwestern University, 2145 Sheridan Road, Evanston, Illinois 60208, United States.

Journal of the American Chemical Society
|August 21, 2024
PubMed
まとめ

研究者らは,HER2+ がんに対するT細胞の再誘導を目的とした新しい双特異性抗体の模倣剤を開発した. これらのMegaMoleculesはがん細胞を効果的に標的にし,臨床前のモデルでは腫瘍の減少につながります.

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