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Updated: Jun 15, 2025

Efficient Synthesis of Polyfunctionalized Benzenes in Water via Persulfate-promoted Benzannulation of α,β-Unsaturated Compounds and Alkynes
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Efficient Synthesis of Polyfunctionalized Benzenes in Water via Persulfate-promoted Benzannulation of α,β-Unsaturated Compounds and Alkynes

Published on: December 16, 2019

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メタベンゼンイソステルの触媒的非対称合成

Mingkai Zhang1, Matthew Chapman1, Bhagyesh R Sarode2

  • 1Department of Chemistry, Boston College, Chestnut Hill, MA, USA.

Nature
|August 21, 2024
PubMed
まとめ

研究者は,単純な前体からキラル・ノートリサイクランを生成する新しいパラジウム触媒反応を開発した. これらの化合物は,薬剤発見のための効果的な非芳香性イソステルとして機能し,改善された性質とステレオ化学に依存する活性を提供します.

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