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Updated: Jun 15, 2025

Sequencing of mRNA from Whole Blood using Nanopore Sequencing
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次世代のシーケンシングチップでの単分子ダイナミクスの大規模な並列分析

J Aguirre Rivera1, G Mao1, A Sabantsev1

  • 1Department of Cell and Molecular Biology, Science for Life Laboratory, Uppsala University, 75105 Uppsala, Sweden.

Science (New York, N.Y.)
|August 22, 2024
PubMed
まとめ

図書館スケールでの多重化単分子特性 (MUSCLE) は,大規模なDNA分析を可能にします. この新しい方法は 顕微鏡と配列を組み合わせて 複雑な生物学的動態を明らかにし DNAの新しい振る舞いを明らかにします

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DNA sequencing is a fundamental technique that is routinely used in the biological sciences. This method can be applied to a range of questions at different scales - from the sequencing of a cloned DNA fragment or the study of a mutation in a gene up to whole-genome sequencing. However, despite the widespread use of sequencing today, it was not until 1977 that Fredrick Sanger and his collaborators developed the chain-termination method to decode DNA sequences. It relies on the separation of a...
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