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Updated: Jun 14, 2025

Tailoring In Vivo Cytotoxicity Assays to Study Immunodominance in Tumor-specific CD8+ T Cell Responses
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CD8 CAR T細胞における不対称な細胞分裂による宿命誘導

Casey S Lee1,2, Sisi Chen1,2, Corbett T Berry1,2

  • 1Department of Dermatology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.

Nature
|August 28, 2024
PubMed
まとめ

チメリック抗原受容体T細胞 (CARTs) の非対称な細胞分裂は,異なる細胞運命を決定する. この発見は,CARTがどのように差別化されるかを明らかにし,がん治療の有効性を高めるための新しい枠組みを提供します.

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