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Updated: Jun 14, 2025

Deciphering Molecular Mechanism of Histone Assembly by DNA Curtain Technique
06:32

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Fanzorの多様性とDNA分裂メカニズムに関する構造的な洞察

Peiyu Xu1, Makoto Saito1, Guilhem Faure1

  • 1Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; McGovern Institute for Brain Research at MIT, Cambridge, MA 02139, USA; Department of Brain and Cognitive Science, Massachusetts Institute of Technology, Cambridge, MA 02139, USA; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA; Howard Hughes Medical Institute, Cambridge, MA 02139, USA.

Cell
|August 29, 2024
PubMed
まとめ

Fanzor (Fz) エンドヌクレアスは,種間の遺伝子編集のために共通のRNAインターフェースを使用します. 構造分析により 精密なゲノム操作のための DNAの結合と解き放たれと ユニークな触媒メカニズムが明らかになりました

キーワード:
DNA分裂メカニズムファンゾールRループ構造アクティベーションメカニズム触媒部位ユカリオットRNA誘導DNAエンドヌクレアース遺伝子編集構造的な多様性

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