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Updated: Jun 13, 2025

Investigating the Pathogenesis of MYH7 Mutation Gly823Glu in Familial Hypertrophic Cardiomyopathy using a Mouse Model
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LMNA Q353R変異は,ビタミンDシグナル伝達障害による拡張性心筋病を引き起こす

Masamichi Ito1,2, Manami Katoh1,3,4, Tatsuro Sassa1

  • 1Department of Cardiovascular Medicine (M. Ito, M. Katoh, T.S., T.K., K.F., S.Y., M. Katagiri, M. Kubota, T.Y., S.H., H.M., S.N., I.K.), Graduate School of Medicine, The University of Tokyo, Bunkyo-ku, Japan.

Circulation
|September 16, 2024
PubMed
まとめ

No abstract available in PubMed .

キーワード:
DNA 損傷心筋細胞拡大心筋病薬物スクリーニング心不全人間の誘発性多能幹細胞ビタミンD

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Satellite Stem Cells and Muscular Dystrophy01:21

Satellite Stem Cells and Muscular Dystrophy

Satellite stem cells or myosatellite cells are quiescent stem cells that Alexander Mauro first identified in 1961. These cells are located between the sarcolemma, the plasma membrane of muscle fibers, and the basal lamina, the connective tissue sheath covering it. These mononucleated cells are activated in response to muscle injury, can transform into myoblasts, and may form or repair muscle fibers. Myosatellite cells can provide additional myonuclei for muscle regeneration or return to a...
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Translation

Lesson: Translation
Translation is the process of synthesizing proteins from the genetic information carried by messenger RNA (mRNA). Following transcription, it constitutes the final step in the expression of genes. This process is carried out by ribosomes, complexes of protein and specialized RNA molecules. Ribosomes, transfer RNA (tRNA), and other proteins produce a chain of amino acids—the polypeptide—as the end product of translation.
Translation Produces the Building Blocks of...
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