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Updated: Jun 12, 2025

Identification of Small Molecule-binding Proteins in a Native Cellular Environment by Live-cell Photoaffinity Labeling
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Identification of Small Molecule-binding Proteins in a Native Cellular Environment by Live-cell Photoaffinity Labeling

Published on: September 20, 2016

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薬物標的の識別のためのフォトリレーザブルラベルとしてのオキサディアゾリン

Corentin Bon1, Benedikt Goretzki2, Marie Flamme3

  • 1Global Discovery Chemistry, Novartis Biomedical Research, Novartis Pharma AG, Basel 4056, Switzerland.

Journal of the American Chemical Society
|September 17, 2024
PubMed
まとめ

オクサジアゾリンは,伝統的なディアジリンの限界を克服する,新しいフォトアフィニティラベリング方法を提供します. これらのラベルは,タンパク質の共性改変を in vitro および 細胞内で化学的互換性を向上させる.

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