関連する実験動画

Updated: Jun 12, 2025

Studying TGF-β Signaling and TGF-β-induced Epithelial-to-mesenchymal Transition in Breast Cancer and Normal Cells
06:54

Studying TGF-β Signaling and TGF-β-induced Epithelial-to-mesenchymal Transition in Breast Cancer and Normal Cells

Published on: October 27, 2020

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ダイナミックアロステリーは,オトクリンおよびパラクリンTGF-βシグナリングを駆動する

Mingliang Jin1, Robert I Seed2, Guoqing Cai2

  • 1Department of Biochemistry and Biophysics, University of California, San Francisco (UCSF), San Francisco, CA, USA.

Cell
|September 17, 2024
PubMed
まとめ

変形成長因子β (TGF-β) は,その潜伏複合体から放出せずにシグナルを出すことができます. この発見は既存のモデルに異議を唱え,TGF-β3の特徴的な機能を説明し,免疫と発達研究に影響を与えています.

キーワード:
TGF-bシグナリングTGF-b1 についてTGF-b3 についてアクティベーションオトクリン信号avb8インテグリンダイナミックアロステリーエントロピーの再分配フリン遅延時間パラクリン信号規制T細胞単粒子の冷凍-EM

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