関連する実験動画

Updated: Jun 12, 2025

Inner Mitochondrial Membrane Sensitivity to Na+ Reveals Partially Segmented Functional CoQ Pools
05:27

Inner Mitochondrial Membrane Sensitivity to Na+ Reveals Partially Segmented Functional CoQ Pools

Published on: July 20, 2022

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哺乳類のミトコンドリアの膜ポテンシャルを制御するトランスミトコンドリアナトリウムグラデント

Pablo Hernansanz-Agustín1, Carmen Morales-Vidal2, Enrique Calvo3

  • 1Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC), Madrid 28029, Spain; Centro de Investigación Biomédica en Red de Fragilidad y Envejecimiento Saludable, Madrid, Spain.

Cell
|September 20, 2024
PubMed
まとめ

ナトリウムイオン (Na+) は,陽子 (H+) とともに,ミトコンドリア膜ポテンシャル (ΔΨmt) に大きく貢献する. この研究は,細胞エネルギーに不可欠なミトコンドリア複合体Iにおける新しいNa+/H+交換器を特定し,レベルの遺伝光神経病に関与しています.

キーワード:
LHON についてNa(+) グラデーション複合体 IミトコンドリアのNa(+) /H(+) 反ポーターΔΨmt について

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