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Updated: Jun 12, 2025

Investigating the Spreading and Toxicity of Prion-like Proteins Using the Metazoan Model Organism C. elegans
12:57

Investigating the Spreading and Toxicity of Prion-like Proteins Using the Metazoan Model Organism C. elegans

Published on: January 8, 2015

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ポリメリックアンタゴニストと変異によって調節される液体-液体相分離後の細胞プリオンタンパク質の構成変化

Yangyi Liu1,2, Marcus D Tuttle1, Mikhail A Kostylev2

  • 1Department of Chemistry, Yale University, 225 Prospect Street, New Haven, Connecticut 06511, United States.

Journal of the American Chemical Society
|September 26, 2024
PubMed
まとめ

プリオンタンパク質 (PrPC) の液体-液体相分離 (LLPS) には成熟プロセスが含まれています. この形状の変化は 変異とPSCMAによって加速され 神経退化を引き起こす可能性があります

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Monitoring Cell-to-cell Transmission of Prion-like Protein Aggregates in Drosophila Melanogaster10:26

Monitoring Cell-to-cell Transmission of Prion-like Protein Aggregates in Drosophila Melanogaster

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Screening for Amyloid Aggregation by Semi-Denaturing Detergent-Agarose Gel Electrophoresis

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