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Updated: Jun 11, 2025

Synthesis of Esters Via a Greener Steglich Esterification in Acetonitrile
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ニトロンC-H挿入によるα-アミノエステルの生物触媒合成

Edwin Alfonzo1, Deirdre Hanley1, Zi-Qi Li1

  • 1Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, California 91125, United States.

Journal of the American Chemical Society
|September 27, 2024
PubMed
まとめ

研究者はエステルの直接的なα-C-Hアミナ化のための新しい酵素を開発し,貴重なα-アミノエステルを作成した. 誘導演化によりこれらの酵素は,温和な条件下での幅広い基板範囲とエナチオ選択性を強化した.

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