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Updated: Jun 11, 2025

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β1アドレネルゲン受容体の結合と活性化 - 第三の細胞内ループの役割

Xingyu Qiu1,2, Kin Chao3, Siyuan Song1,2

  • 1Physical and Theoretical Chemistry Laboratory, Department of Chemistry, University of Oxford, Oxford, OX1 3QZ, U.K.

Journal of the American Chemical Society
|October 3, 2024
PubMed
まとめ

β1アドレネルゲン受容体 (β1AR) の細胞内ループ3 (ICL3) は,ニュクレオチド放出後にGs結合を微妙に変化させ,cAMPの産生を刺激するが,GDPの放出を刺激しない.

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