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Updated: Jun 11, 2025

Correlative Microscopy for 3D Structural Analysis of Dynamic Interactions
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クリオ・エム 対 病気 X

Fasséli Coulibaly1

  • 1Biomedicine Discovery Institute, Monash University, Clayton, VIC, Australia; Department of Biochemistry and Molecular BIology, Monash University, Clayton, VIC, Australia.

Cell
|October 4, 2024
PubMed
まとめ

クリオ電子顕微鏡 (cryo-EM) で,養殖スーパーワームに感染する病気の原因が特定されました. この技術はスーパーワームの養殖産業の 診断と予防戦略を 進歩させています

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Conventional electron microscopy (EM) involves dehydration, fixation, and staining of biological samples, which distorts the native state of biological molecules and results in several artifacts. Also, the high-energy electron beam damages the sample and makes it difficult to obtain high-resolution images. These issues can be addressed using cryo-EM, which uses frozen samples and gentler electron beams. The technique was developed by Jacques Dubochet, Joachim Frank, and Richard Henderson, for...
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