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Updated: Jun 11, 2025

Using Reverse Genetics to Manipulate the NSs Gene of the Rift Valley Fever Virus MP-12 Strain to Improve Vaccine Safety and Efficacy
09:13

Using Reverse Genetics to Manipulate the NSs Gene of the Rift Valley Fever Virus MP-12 Strain to Improve Vaccine Safety and Efficacy

Published on: November 1, 2011

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リフトバレー熱ウイルスは,ウイルスの複製を促進するプログラム可能なE3リガースの組み立てを調整する

Huiling Li1, Yulan Zhang2, Guibo Rao2

  • 1State Key Laboratory of Virology, Wuhan Institute of Virology, Center for Antiviral Research, Chinese Academy of Sciences, Wuhan 430071, People's Republic of China; University of Chinese Academy of Sciences, Beijing 100049, People's Republic of China.

Cell
|October 4, 2024
PubMed
まとめ

リフトバレー熱ウイルスの非構造タンパク質NSsは,繊維状のE3リガスを形成する. この機械は細胞のTFIIHを分解し,抗ウイルス免疫を抑制し,ウイルス病原性を促進します.

キーワード:
FBXO3 についてIFN-Iの応答NSs についてRVFVTFIIH について糸状E3リガゼタンパク質分解剤

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Methodology for the Efficient Generation of Fluorescently Tagged Vaccinia Virus Proteins09:27

Methodology for the Efficient Generation of Fluorescently Tagged Vaccinia Virus Proteins

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