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Updated: Jun 11, 2025

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小分子アセンブリアゴニストは,B型肝炎ウイルスの核タンパク質ディマーとカプシドの動態を変えます

Ravi Kant1,2, Lye-Siang Lee3, Angela Patterson3

  • 1Department of Chemistry and Biochemistry, Montana State University, Bozeman, Montana 59717, United States.

Journal of the American Chemical Society
|October 9, 2024
PubMed
まとめ

カプシドアセンブリモジュール (CAM) は,B型肝炎ウイルス (HBV) の二元構造を破壊し,ウイルスのカプシドを安定させる. これは,CAMがHBVの集合と感染を制御するためにアロステリックネットワークを利用できることを明らかにしています.

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